Sumana Srivatsa
Postdoctoral researcher
Stanford University
I am an SNSF postdoctoral fellow at Stanford Center for Population Health Sciences, Palo Alto. My research interests lie at the intersection of personalised medicine, causality, public health, and policy. I work on large-scale EHR and claims data to establish the causal effects of clinical interventions with a focus on treatment effects variations across patient subgroups. I received my PhD in computational biology from ETH Zurich. My thesis leveraged interventional and observational data for learning causal interactions in cancer and infectious diseases.
Besides my academic life, I am an avid traveller, a movie buff, and enjoy the outdoors. I also enjoy reading, painting, and quizzing.
Research
During my PhD, I focussed on developing methods based on principles from probabilistic graphical models, computational statistics, and causal inference for analysing large scale perturbation screens data. Here you can find a list of my relevant publications.
- H. Montazeri, M. Coto-Llerena, G. Bianco, E. Zangeneh, S. Taha-Mehlitz, V. Paradiso, S. Srivatsa, A. de Weck, G. Roma, M. Lanzafame, M. Bolli, N. Beerenwinkel, M. von Flue, LM. Terracciano, S. Piscuoglio, CKY. Ng (2021). Systematic identification of novel cancer genes through analysis of deep shRNA perturbation screens, Nucleic Acids Research, doi: 10.1093/nar/gkab627.
- G. Bianco, M. Coto-Llerena, J. Gallon, S. Taha-Mehlitz, V. Kancherla, M. Konantz, S. Srivatsa, H. Montazeri, M. De Menna, V.P aradiso, C. Ercan, N. Beerenwinkel, M. Kruithof-de Julio, L.M. Terracciano, C. Lengerke, R.M. Jeselsohn, C.K.Y. Ng, S. Piscuoglio (2020). GATA3 and MDM2 are synthetic lethal in estrogen receptor-positive breast cancers , In revision, Preprint bioRxiv: 10.1101/2020.05.18.\-101998.
- T. Ringel, N. Frey, F. Ringnalda, S. Janjuha, S. Butz, S. Cherkaoui, S. Srivatsa, M. Pirkl, G. Russo, G. Rogler, L. Villiger, N. Beerenwinkel, N. Zamboni, T. Baubec, G. Schwank (2020). Genome-scale CRISPR screening in human intestinal organoids identifies drivers of TGF-β resistance, Cell Stem Cell, doi: 10.1016/j.stem.2020.02.007.
- S. Srivatsa✢, H. Montazeri✢, G. Bianco, M. Coto-Llerena, S. Piscuoglio, CKY. Ng, N. Beerenwinkel (2019). Discovery of synthetic lethal interactions from large-scale pan-cancer perturbation screens , In revision, Preprint bioRxiv: 10.1101/810374.
- S. Srivatsa , J. Kuipers, F. Schmich, S. Eicher, M. Emmenlauer, C. Dehio, N. Beerenwinkel (2018). Improved pathway reconstruction from RNA interference screens by exploiting off-target effects, Bioinformatics, doi: 10.1093/bioinformatics/bty240.
- C. Wang, F. Schmich, S. Srivatsa, J. Weidner, N. Beerenwinkel, A. Spang (2018). Context-dependent deposition and regulation of mRNAs in P-bodies, eLife, doi: 10.7554/eLife.29815.
✢ Authors contributed equally
Notes
I maintain a blog to share my academic and personal experiences. On the academic front, I am mainly using the platform to share my notes. It’s pretty sparse right now but there’ll be more soon.
Gallery
I love travelling and the outdoors. I am not into photography but these are a few snaps from my adventures so far.
I find colors and art very soothing. Under the tutelage of Mrs. Kamala Sundar, I learned the traditional art of Thanjavur painting. Here are a few pictures of my work so far.
